The University of Sherbrooke is at the heart of one of Quebec's three major research centers. Recognized for its sense of innovation, UdeS is a leading partner of higher and regional governments to promote social, cultural and economic development. It also stands out for the strong growth of its research activities in recent years, its success in technology transfer as well as its initiatives in terms of entrepreneurship and open innovation in collaboration with industrial and social circles. 

The university has five campuses, namely Main Sherbrooke Campus, Longueuil Campus, The Health Campus, The Joint Campus in Saguenay (on the site of the Université du Québec à Chicoutimi) and The Joint Campus in Moncton (on the site of the Université de Moncton, in Moncton, New Brunswick) . The main Campus includes most of the faculties and centers, the management of the institution and the support services. 

The Main Campus  and  the Health Campus are both located in Sherbrooke, a city that is approximately 140 kilometers east of Montreal and 50 kilometers north of the US border. The Health Campus, also located in Sherbrooke, houses the Faculty of Medicine and Health Sciences and several partners in the field of biomedical research and clinical intervention. The Longueuil Campus of the Université de Sherbrooke offers more than 120 undergraduate, graduate and postgraduate study programs. Several programs are offered part-time in the evenings and on weekends or in various intensive forms, allowing students to remain in the workforce while studying. Customized training and professional development seminars are also offered to meet very specific needs.

The Main Campus has two complexes housing university residences. The G residences are located at the foot of Mount Bellevue, surrounded by nature and offer a breathtaking view of the city of Sherbrooke. They include 389 rooms, including 30 with a double bed where it is possible to live as a couple, distributed in 13 different blocks.

The E residences are located near the Student Life Pavilion, the Multifunctional Pavilion, the Faculty of Education and the Faculty of Letters and Human Sciences. The E residences have 333 small single rooms and 18 large single rooms, all this, in the heart of the main campus!

During the winter and the summer season, from mid-January to mid-August, the residences of the University of Sherbrooke offer hotel accommodation .

Students registered in the Réussir course or in an educational activity offered before the start of the fall term must request a room reservation.